Endocrine Abstracts

A 27-year-old female presented with severe lethargy; she was found to have hypercalcaemia with corrected calcium of 3.27 mmol/L and biochemistry suggestive of primary hyperparathyroidism (PTH–64.7 umol/L [1.5–7.5 pmol/L]). She had no notable family history of endocrinopathies or malignancies. Imaging suggested two possible parathyroid adenomas at the upper and lower poles of the posterior right lobe of the thyroid and she was referred for surgical intervention. Intra...

A 39-year-old lady presented with chest infection and was found to be hyponatraemic (114 mmol/l) during her third pregnancy. Short synacthen test (SST) revealed inappropriately low ACTH (39 ng/l) with adrenocortical failure (cortical 163, 355, 503 at 0, 30 and 60 min respectively). She was started on replacement hydrocortisone. Adrenal autoantibodies were negative. Other tests showed IGF-1 14.8 (13–50 ηmol/l), growth hormone <0.1 (<10 mU/l), prolactin 677 (&#...